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Are isomalto oligosaccharides natural?

4 min read

While isomalto-oligosaccharides (IMOs) are found naturally in small quantities in foods like honey and miso, the vast majority used in food products today are commercially manufactured. This crucial distinction challenges the perception of IMOs as purely natural ingredients, prompting a closer look at their origin and processing.

Quick Summary

IMOs exist naturally in trace amounts within some fermented foods and honey but are primarily produced industrially through enzymatic processes from starches like corn or tapioca. The source and production method significantly impact their final composition and physiological effects, especially concerning their glycemic response and classification as dietary fiber.

Key Points

  • Limited Natural Presence: Isomalto-oligosaccharides occur naturally in trace amounts in certain foods like honey, miso, and soy sauce, but not in sufficient quantities for large-scale use.

  • Industrial Production Process: Most IMOs on the market are produced commercially from plant starches like corn or tapioca through a multi-step enzymatic process.

  • Enzymatic Conversion: The industrial process uses enzymes like transglucosidase to convert starch into IMOs, creating digestion-resistant bonds not found in the same concentration in nature.

  • Variable Digestibility: Commercial IMOs have been shown to be partially digestible, sometimes raising blood sugar and insulin levels, unlike claims suggesting they function as a zero-calorie fiber.

  • Regulatory Classification: Some regulatory bodies, like the U.S. FDA, do not recognize manufactured IMOs as a dietary fiber, challenging product claims based on their fiber content.

  • Different Composition: The molecular structure and degree of polymerization of manufactured IMOs can differ significantly from their natural counterparts, affecting their physiological impact.

In This Article

Understanding Isomalto-Oligosaccharides

Isomalto-oligosaccharides (IMOs) are a type of short-chain carbohydrate, or oligosaccharide, composed of glucose units linked together. They have gained popularity in the food industry as a lower-calorie, prebiotic fiber alternative to sugar. Their appeal stems from their sweet taste, fiber-like properties, and ability to ferment in the large intestine, feeding beneficial gut bacteria. However, confusion often arises regarding their origin, and the term “natural” is frequently misused or misunderstood when it comes to the IMOs found in many modern food products.

The Natural Presence of IMOs

IMOs do occur in nature, but their presence is limited and they are not abundant. For example, trace amounts can be found in a few traditional fermented foods and natural sweeteners.

  • Fermented Foods: IMOs are a minor component of certain fermented products, including:
    • Soy sauce
    • Miso
    • Sake
    • Sourdough bread
  • Natural Sweeteners: A form of isomaltose, a disaccharide and component of IMO, can also be identified in honey.

The key takeaway is that the concentrations of IMOs in these natural sources are too low to be a practical or economical source for large-scale food manufacturing.

The Manufacturing Process for Commercial IMOs

Due to the impracticality of extracting IMOs from natural sources, the commercial market relies on a multi-step, enzymatic manufacturing process. The starting materials are starches from common agricultural crops.

  1. Starch Liquefaction: Raw starch, often from corn, tapioca, or peas, is treated with enzymes like α-amylase to begin breaking down its long polysaccharide chains.
  2. Saccharification: Additional enzymes, such as β-amylase and pullulanase, further hydrolyze the liquefied starch into a high-maltose syrup containing di-, tri-, and oligosaccharides.
  3. Transglycosylation: A specific enzyme, transglucosidase, is introduced to rearrange the linkages between the glucose units. This process converts the more easily digestible α-1,4 linkages into digestion-resistant α-1,6 linkages, which is the defining characteristic of IMOs.
  4. Purification: The resulting IMO syrup is then purified to remove unwanted byproducts and concentrate the final product.

This industrial process creates a product with a different composition and degree of polymerization (DP) than the trace amounts found in natural foods. The specific enzyme cocktails and processing conditions can vary between manufacturers, leading to differences in the final product's properties, including digestibility and prebiotic effect.

Natural vs. Commercial Isomalto-Oligosaccharides: A Comparison

Feature Naturally Occurring IMOs Commercially Manufactured IMOs
Source Found in trace amounts in fermented foods (miso, soy sauce) and honey. Produced industrially from plant starches (corn, tapioca, pea).
Availability Extremely limited; not a viable source for industrial use. Mass-produced in large quantities for widespread food manufacturing.
Processing Formed during natural fermentation processes. Created through a multi-step, controlled enzymatic conversion of starch.
Composition Varies depending on the source food and natural process. Standardized composition, but can vary by manufacturer and enzymatic cocktail used.
Regulatory Status Regarded simply as a minor component of a whole food. Must be approved for use as a food ingredient, often categorized as a novel food.
Glycemic Impact Not a significant factor due to trace quantities in whole foods. Research shows varying glycemic impact; some can significantly raise blood glucose, challenging low-glycemic claims.

The Impact on Nutritional Labeling and Health Claims

The manufactured nature of commercial IMOs has significant implications for how they are perceived and labeled. The U.S. FDA, for example, has rejected petitions to include IMO on the official dietary fiber list, partly because evidence regarding its beneficial physiological effects was deemed insufficient for all product variants. This raises questions about the fiber content claimed on many food products, particularly protein bars, that use manufactured IMOs as a main ingredient. Consumers relying on these labels for carbohydrate counting or glycemic control may be misled, as commercial IMOs can be partially digested and may elevate blood sugar and insulin levels.

The Importance of Source and Context

When considering isomalto-oligosaccharides, it is critical to differentiate between the trace amounts found intrinsically in certain whole foods and the manufactured versions added as ingredients. While the industrial enzymatic process begins with natural starches, the extensive modification and processing mean the final product is more accurately described as a modified or manufactured ingredient, rather than simply “natural”. The context—whether consumed as a minor part of a whole food or as a concentrated ingredient—is vital for understanding its true nutritional and physiological impact. The health benefits, including prebiotic effects, largely depend on the specific composition and degree of polymerization, which can differ markedly between natural and commercial versions.

Conclusion

To answer the question, "Are isomalto oligosaccharides natural?", the answer is nuanced: yes and no. They exist naturally in very small amounts within certain fermented foods like miso and honey. However, the product most consumers encounter in packaged foods is an industrially manufactured ingredient made from plant starches through a multi-step enzymatic process. This distinction is vital for understanding its nutritional profile, particularly as commercial IMOs have been shown to have a variable glycemic response and are not universally recognized as dietary fiber by some regulatory bodies. Therefore, while derived from natural sources, the commercial product is an engineered food additive rather than a truly natural one, and consumers should be aware of this difference when evaluating products containing them.

Frequently Asked Questions

The primary difference lies in their quantity and origin. Natural IMOs are found in small, trace amounts in foods like honey, while commercial IMOs are mass-produced through an industrial enzymatic process using starch from plants like corn.

No. The IMOs added to food products are manufactured ingredients, not whole, natural fiber. The U.S. FDA, for example, has rejected requests to label manufactured IMOs as dietary fiber due to inconclusive evidence regarding their physiological benefits in all forms.

Yes. While often marketed as a low-glycemic ingredient, some studies have shown that manufactured IMOs can be partially digested and may cause a rise in blood glucose and insulin levels, especially in concentrated syrup form.

Natural sources include traditional fermented foods like miso, soy sauce, and sake, as well as honey. However, the amounts present in these foods are minimal and not concentrated like commercial versions.

The process uses naturally occurring enzymes to act on natural starches, but the overall procedure is an industrial, manufactured process designed for high-yield production, making the end product not truly 'natural' in the conventional sense.

The distinction is important because it affects nutritional expectations. Manufactured IMOs may not have the same health effects as natural ones and could impact blood sugar, which is crucial for those managing diabetes or following low-carb diets.

No, the effects can vary. The specific composition and degree of polymerization in commercial IMO products differ based on the manufacturing methods used, which in turn influences their digestibility and prebiotic activity.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.