Category: Drug development

Approximately 90% of all human pharmaceuticals globally are oral formulations, making it essential to understand what best describes bioavailability and its impact on drug efficacy. Bioavailability is the rate and extent to which an active drug ingredient is absorbed and becomes available at its site of action within the body.

Research indicates that the absolute oral bioavailability of a drug can be significantly less than 100% due to various physiological hurdles. Understanding what factors affect oral bioavailability is crucial for pharmacists, clinicians, and researchers to ensure medication efficacy and optimize treatment outcomes.