Category: Me cfs

According to a 2024 review, there is inconsistent evidence to classify Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) as a purely autoimmune disease, though a subgroup with an autoimmune component may exist. This uncertainty extends to Post-Exertional Malaise (PEM), the hallmark symptom of ME/CFS, which remains a subject of intense scientific investigation into its underlying causes.

According to the Bateman Horne Center, continually pushing through Post-Exertional Malaise (PEM) without proper rest can lead to a lasting reduction in overall functional ability. The long term effects of PEM extend far beyond temporary fatigue, involving cellular damage, immune system dysfunction, and potentially irreversible neurological and physical decline.