Category: Pellagra

According to the World Health Organization, pellagra remains endemic in some developing countries, particularly where corn is a major food source. This devastating condition is caused by a severe deficiency of niacin (vitamin B3), or its precursor tryptophan, which affects high-energy tissues like the skin, digestive tract, and nervous system.

Historically prevalent in regions relying heavily on corn-based diets, pellagra is a severe nutritional disorder marked by the infamous '4 Ds'. The answer to the question, **Which vitamin deficiency is associated with the 4 Ds?**, is a severe lack of niacin, or vitamin B3, which is critical for cellular energy and repair.