How Is Artificial B12 Made? The Intricate Process of Microbial Fermentation
                                
                                
                                •
                                
                                
                        
                                    
                                    4 min read                                
                            
                                Vitamin B12 biosynthesis is exclusively performed by certain bacteria and archaea, as humans and plants cannot produce it. To meet the global demand for supplements and fortified foods, artificial B12 is produced on a massive scale using a blend of controlled microbial fermentation and precise chemical engineering.