What is the disease known as pellagra?
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4 min read
Pellagra, from the Italian for 'rough skin', is a nutritional disease that historically plagued populations with limited diets. It is defined as a systemic illness resulting from a severe deficiency of niacin (vitamin B3) or its precursor, tryptophan. While once epidemic, especially in the American South, the disease is now rare in developed countries but persists in regions with food insecurity.