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Foods That Contain Phenylethylamine (PEA) and Its Precursor

4 min read

Despite phenylethylamine's (PEA) reputation as the "love chemical," studies indicate that the PEA found in chocolate is metabolized rapidly by the body, limiting its effect on brain chemistry. This natural monoamine is found in various food sources, particularly those that have undergone fermentation, and can also be synthesized by the body from the amino acid L-phenylalanine.

Quick Summary

Phenylethylamine, a naturally occurring trace amine, is present in foods like chocolate and fermented items, and can be produced from the amino acid phenylalanine. Its effects from dietary consumption are minimal due to rapid metabolism.

Key Points

  • Chocolate is a source: Cocoa beans and chocolate contain PEA, but the amount is too small and quickly metabolized to have a significant mood-altering effect.

  • Fermented foods contain PEA: Natto, some cheeses, and fermented meats naturally contain PEA due to microbial activity during their production.

  • L-Phenylalanine is a precursor: The body synthesizes PEA from the essential amino acid L-phenylalanine, found in protein-rich foods like meat, eggs, and legumes.

  • Dietary PEA is quickly broken down: Enzymes in the small intestine rapidly metabolize PEA from food, preventing it from reaching the brain in high concentrations.

  • Supplements offer concentrated doses: PEA is available in supplement form, but high doses carry a risk of side effects, including rapid heart rate and anxiety.

  • Not the same as palmitoylethanolamide: Phenylethylamine (PEA) should not be confused with palmitoylethanolamide (also PEA), a fatty acid derivative with different effects.

  • Risks for some individuals: High-dose PEA can be risky for individuals with certain health conditions or those taking specific medications like MAOIs.

In This Article

Direct Dietary Sources of Phenylethylamine

While often associated with chocolate, phenylethylamine (PEA) is also present in other foods, especially those produced through microbial action. Fermentation by certain bacteria and fungi increases the content of biogenic amines, including PEA. However, the amount absorbed from these sources is generally small due to the body's efficient metabolic processes.

Fermented Foods

Fermented products are among the most common direct sources of PEA and other biogenic amines. Examples include:

  • Natto: This traditional Japanese dish of fermented soybeans is a known source of PEA.
  • Wine: Both red and white wines can contain PEA, with levels influenced by grape quality and fermentation methods.
  • Certain cheeses: Some varieties of aged or fermented cheeses may contain PEA, though levels can vary significantly.
  • Fermented meats: Products like salami can contain PEA, as can other fermented meat products.
  • Tofu-misozuke: A traditional Japanese fermented tofu aged in miso has been studied for its aromatic amine content.

Cocoa and Chocolate

Chocolate is arguably the most famous food source of PEA. The compound is naturally present in cocoa beans, and its concentration can increase during the fermentation and roasting processes. However, the PEA from chocolate is quickly broken down by enzymes in the digestive system before it can reach the brain in significant quantities to produce a psychoactive effect. The mood-boosting sensation from chocolate is more likely due to a combination of other compounds, sugar, and fat.

Blue-Green Algae

Blue-green algae, also known as cyanobacteria, is another natural source of phenylethylamine. It is sometimes consumed as a supplement, though like other dietary sources, the PEA content is subject to rapid metabolism.

Foods Containing the Precursor: L-Phenylalanine

Since the body can synthesize its own PEA from the amino acid L-phenylalanine, consuming foods rich in this precursor can indirectly influence PEA production. L-phenylalanine is an essential amino acid, meaning the body cannot produce it and must obtain it from food. Foods rich in L-phenylalanine are typically protein-dense. Here are some examples:

  • Meats and poultry: Beef, chicken, turkey, lamb, and pork are all excellent sources of L-phenylalanine.
  • Dairy products: Milk, cheese, and yogurt contain this amino acid.
  • Eggs: A well-known source of all essential amino acids, including L-phenylalanine.
  • Nuts and seeds: Almonds, peanuts, and pumpkin seeds are good plant-based sources.
  • Legumes: Lentils, chickpeas, soybeans, and other beans are rich in L-phenylalanine.

Phenylethylamine Supplements

For those seeking a more concentrated dose of PEA, dietary supplements are available in capsule or powder form, often as phenylethylamine hydrochloride (HCL). The advantage of supplements is that they provide a much higher dose than is typically found in food. When taken orally, a significant amount is still metabolized by monoamine oxidase B (MAO-B) enzymes in the small intestine, but with high doses, some PEA can reach the brain. However, this can also lead to side effects like rapid heart rate, anxiety, and agitation.

Comparison of Phenylethylamine Sources

Feature Dietary Sources (Food) Supplemental PEA (HCL) Endogenous Production
PEA Concentration Trace amounts High, concentrated doses Variable, regulated by the body
Main Component Direct PEA or L-Phenylalanine Phenylethylamine HCL Synthesized from dietary L-Phenylalanine
Psychoactive Effects Negligible due to rapid metabolism Possible at high doses, but with risk of side effects Normal regulatory function; not a psychoactive source
Risks/Side Effects Generally safe for most people Rapid heart rate, anxiety, agitation at high doses None associated with normal body function
Regulation Not regulated as a concentrated source Unregulated as dietary supplement Tightly regulated by the body's enzymes

Important Considerations and Risks

While dietary phenylethylamine is generally safe, the use of concentrated supplements carries certain risks and is not for everyone. Individuals with conditions like bipolar disorder or schizophrenia should be cautious, as PEA could worsen symptoms. The compound can also interact dangerously with antidepressant medications, particularly MAOIs, by causing an excessive buildup of serotonin. It is also important not to confuse phenylethylamine (PEA) with palmitoylethanolamide (also called PEA), a fatty acid derivative with different effects. Always consult a healthcare provider before taking PEA supplements. For further reading on the chemical properties and psychological effects of PEA, a resource like McGill University's Office for Science and Society offers insightful information regarding misconceptions surrounding the compound in chocolate, accessible at https://www.mcgill.ca/oss/article/history-general-science/phenylethylamine-said-stroke-fire-love-here-comes-water-bucket.

Conclusion

In summary, phenylethylamine (PEA) can be found in a variety of food sources, including fermented products like cheese and natto, as well as cocoa. Furthermore, the body can produce PEA from the essential amino acid L-phenylalanine, which is abundant in protein-rich foods such as meat, dairy, and legumes. However, the amount of PEA ingested from food is too small and is metabolized too quickly to have a significant stimulating or mood-altering effect on the brain. For this reason, the perception of chocolate as a potent mood enhancer due to its PEA content is largely unfounded. While concentrated PEA supplements exist and may have some effects, they also carry risks and are rapidly broken down by the body, so their use should be approached with caution and medical consultation. The most reliable way to maintain healthy PEA levels is through a balanced diet rich in its precursor, L-phenylalanine.

Frequently Asked Questions

While levels vary, fermented foods like natto, some cheeses, and certain types of wine contain phenylethylamine (PEA). The PEA content in chocolate is often cited but is metabolized too quickly to be potent from dietary intake.

No, the mood-boosting effects of chocolate are not primarily caused by its phenylethylamine (PEA) content. The body breaks down PEA from chocolate almost immediately, preventing it from reaching the brain in sufficient amounts to influence mood.

L-phenylalanine is an essential amino acid that serves as a precursor for the body to produce phenylethylamine (PEA). Phenylalanine is obtained from protein-rich foods, whereas PEA is the trace amine that the body creates from it.

Phenylethylamine supplements can cause side effects like rapid heart rate and anxiety, especially at high doses. It is potentially unsafe for individuals with bipolar disorder, schizophrenia, or those taking MAOI antidepressants, and medical advice should always be sought before use.

Individuals with the rare genetic disorder phenylketonuria (PKU) cannot properly metabolize phenylalanine and must follow a specific low-phenylalanine diet to avoid serious health issues.

Yes, exercise has been shown to increase phenylethylamine (PEA) levels in the body. This is believed to contribute to the positive mood effects often associated with physical activity, like a 'runner's high'.

Some individuals, particularly those taking MAOI antidepressants or those sensitive to biogenic amines like phenylethylamine and tyramine, may need to limit fermented foods to avoid adverse reactions.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.