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How do you take cytisine to quit smoking?

3 min read

In a 2014 study published in the New England Journal of Medicine, participants using cytisine combined with behavioral support were more successful at quitting smoking at one and six months compared to those using nicotine-replacement therapy. Taking cytisine correctly, which is a plant-based medication used for smoking cessation, involves following a precise tapering schedule over a specific period to manage nicotine cravings and withdrawal symptoms effectively.

Quick Summary

Cytisine is a prescription medication taken over a set period in a tapering course to help quit smoking. It works by mimicking nicotine's effects, reducing cravings and withdrawal symptoms. Follow the specific daily schedule provided by a healthcare professional and aim to stop smoking completely early in the treatment for best results.

Key Points

  • Follow the Tapering Schedule: Cytisine treatment spans a specific duration, starting with a higher dose that gradually tapers down.

  • Quit Early in Treatment: You must set a firm quit date and stop smoking completely early in the treatment to maximize success and avoid adverse effects.

  • Take Tablets with Water: Ingest each tablet orally with water, as directed by the schedule.

  • Do Not Double Up on Doses: If a dose is missed, do not take a double dose to catch up. Simply take the next scheduled dose as planned.

  • Consult a Doctor for Pre-Existing Conditions: Individuals with cardiovascular problems, liver/kidney issues, or certain psychiatric disorders should consult a healthcare provider before starting.

  • Be Aware of Common Side Effects: Mild side effects like nausea, headaches, and sleep disturbances are possible, especially at the start of the regimen.

In This Article

Understanding the Cytisine Treatment Plan

Cytisine is a non-nicotine, plant-based medication that helps people quit smoking by acting on the brain's nicotine receptors to reduce cravings and withdrawal symptoms. The treatment course typically involves a specific duration, and it is crucial to adhere to the decreasing dosage schedule provided by a healthcare professional. You must set a quit date for smoking early in the treatment period to maximize effectiveness and avoid adverse reactions.

The Step-by-Step Schedule

Cytisine is available in tablet form and should be taken with water. The dose is typically higher at the start to combat initial withdrawal and gradually decreases over the course to help the body adjust. It is often helpful to set phone alarms or reminders to stay on track with the schedule, especially during the initial phase.

Initial Phase: The starting dose is usually taken frequently throughout the day. During this phase, you can continue to smoke but should actively be reducing your cigarette intake.

Tapering Phase: The daily dose decreases over subsequent days. Your quit date (the day of your last cigarette) should be set early in this period. After this, you must not smoke again. The frequency of taking the tablets gradually reduces over the following weeks.

Final Phase: In the final stretch of treatment, the dosage is reduced further to a lower frequency per day.

Important Reminders and Safety Precautions

  • Stay Hydrated: Always take the tablets with a sufficient amount of water.
  • Do Not Double Dose: If you miss a dose, do not take a double dose to compensate. Take the next dose at the regularly scheduled time and continue the regimen.
  • Avoid Smoking After the Set Quit Date: Continuing to smoke after the designated quit date of treatment can increase adverse reactions and negate the benefits of the medication.
  • Seek Medical Advice: If you accidentally take too many tablets, or experience symptoms like nausea, vomiting, breathing problems, or blurred vision, stop taking the medication and seek immediate medical attention.
  • Report Side Effects: Common, milder side effects can include nausea, headaches, and sleep disturbances. If these or any other side effects become bothersome, speak with your healthcare provider.
  • Consult Your Doctor: Before starting cytisine, discuss your medical history, especially if you have heart conditions, liver or kidney problems, or psychiatric disorders.

Comparing Cytisine to Other Smoking Cessation Aids

Feature Cytisine Nicotine Replacement Therapy (NRT) Varenicline (e.g., Champix) Bupropion (e.g., Zyban)
Mechanism Partial agonist of nicotine receptors, mimicking nicotine's effects to reduce cravings. Provides 'clean nicotine' to manage withdrawal symptoms without tobacco. Partial agonist of nicotine receptors, similar to cytisine but a different compound. Antidepressant that affects brain chemistry related to cravings.
Form Oral tablet. Patches, gum, lozenges, inhalers, sprays. Oral tablet (Note: availability may vary). Oral tablet.
Treatment Duration A typical course lasts a specific number of days. Typically several weeks, with gradual reduction. Typically 12 weeks. Typically several weeks.
Effectiveness Shown to be more effective than NRT and placebo in studies. Effective for many, but some studies show cytisine is more so. Generally effective, with similar efficacy to cytisine in some trials. Effective option, often used for those not suitable for other therapies.
Side Effects Most commonly mild gastrointestinal issues, headaches, and sleep problems. Can include skin irritation from patches, or mouth/throat irritation from gum/sprays. May include nausea, headaches, and sleep disorders. Potential for insomnia, dry mouth, and agitation.

Conclusion

Taking cytisine involves a disciplined process that follows a strict decreasing dose schedule over a set period. By beginning treatment with a committed quit date early in the process and adhering to the prescribed plan, individuals can effectively reduce cravings and withdrawal symptoms. It is a powerful tool in the journey to becoming smoke-free, but its success depends on the user’s diligence and consultation with a healthcare professional to ensure safety and proper use. This commitment, coupled with the medication’s effect on nicotine receptors, provides a strong foundation for a successful quit attempt.

Visit the National Centre for Smoking Cessation and Training (NCSCT) website for comprehensive resources and information about cytisine.

Frequently Asked Questions

The typical course lasts a specific number of days, beginning with a higher frequency of tablets daily for the first few days. The dose is then gradually reduced over the remaining days, ending with a lower frequency per day.

You can smoke during the initial days of treatment while your body adjusts. However, you must stop smoking completely by a date set early in the treatment, as continuing to smoke after this point can increase adverse effects.

If you forget a dose, do not take a double dose to compensate. Continue with the next scheduled dose as planned. It is crucial to finish the full course for the treatment to be most effective.

No, cytisine is a prescription-only medication in many countries. You must have a consultation with a healthcare provider to receive a prescription.

While most side effects are mild, severe symptoms like breathing problems or convulsions require immediate medical attention. In such cases, stop taking the medication and seek help.

Yes, cytisine is not recommended for individuals who are pregnant, breastfeeding, or have certain medical conditions such as unstable angina, recent heart attack or stroke, or significant liver or kidney impairment.

It is generally safe to drink alcohol in moderation while taking cytisine, but it is always best to drink sensibly and discuss this with your doctor if you have concerns.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.