How Many Calories Are in a Single Slice of Supreme Pizza?

November 24, 2025 •

4 min read

The calorie count of a single slice of supreme pizza can vary dramatically, ranging from approximately 190 to over 500 calories, influenced heavily by the crust, portion size, and specific toppings. This wide range means that not all supreme slices are created equal, so understanding the variables is key.

Quick Summary

The calorie content of a slice of supreme pizza varies widely based on crust type, serving size, and toppings. Different restaurants and brands can have significant nutritional differences, with estimates typically falling between 190 and over 500 calories per slice.

Key Points

Variable Calorie Count: A single slice of supreme pizza can range from 190 to over 500 calories, depending on the specific recipe, crust, and toppings.
Crust Is Key: Thinner crusts generally have fewer calories than thick or stuffed crusts, which significantly increase the total count.
Toppings Influence Calories: Calorie-dense processed meats like pepperoni and sausage add more calories and fat compared to lower-calorie vegetable toppings.
Size Matters: A larger, heavier slice from a big pizza will naturally contain more calories than a smaller, thinner one.
Restaurant vs. Homemade: The nutritional value varies by brand; making a homemade version offers complete control over ingredients and can be a healthier, lower-calorie option.
Reduce Calories with Smart Swaps: Opting for thin crust, adding more vegetables, using less cheese, or choosing leaner meats are effective strategies to lower the calorie count.

Factors That Affect Supreme Pizza Calorie Counts

Pinpointing an exact number for how many calories are in a single slice of supreme pizza is impossible without knowing the specifics, because several key variables play a major role. These factors determine the final nutritional profile of your slice, impacting everything from fat and carbohydrate content to protein count.

Crust Thickness and Type

The foundation of any pizza, the crust, is one of the most influential factors regarding calorie count. A thin crust, for instance, provides a lower-calorie base than a hand-tossed, deep-dish, or stuffed crust option. Deep-dish and stuffed crusts, in particular, pack significantly more calories due to their denser dough and added cheese, respectively. For example, a regular crust slice from Pizza Hut was found to be around 309 calories, whereas a thin crust slice could be considerably less.

Toppings and Cheese

The 'supreme' label implies a loaded pizza, typically featuring a combination of pepperoni, sausage, onions, bell peppers, and olives. The type and quantity of these toppings directly add to the calorie count. Processed meats like pepperoni and sausage are higher in fat and sodium compared to vegetable toppings, which are low in calories and can add valuable fiber. The amount of cheese is also a major contributor; more cheese equals more fat and calories. For example, a Nutritionix breakdown for a generic supreme pizza shows a range of calories for different components, with sausage and pepperoni contributing a significant portion.

Portion Size and Slices Per Pizza

Not all pizza slices are uniform in size. A large 14-inch pizza cut into eight slices will yield a larger, more calorie-dense slice than the same pizza cut into twelve slices. A personal pan pizza, while appearing smaller, can contain 800 calories or more for the whole pie, meaning a single, larger slice can be very high in calories. This is why it's crucial to check the serving size defined by the restaurant when looking at nutritional information.

Comparison of Supreme Pizza Calorie Estimates

The table below illustrates the wide calorie range you can expect from a slice of supreme pizza, based on different restaurant data and general estimates.


Pizza Type / Brand	Estimated Calories per Slice	Key Factor	Source
Pizza Hut Super Supreme (Regular Crust)	~305–309 kcal	Standard crust, generous toppings	OSF Health Library
Pizza Hut Supreme (Hand-Tossed, 1/8th slice)	~380 kcal	Higher calories due to dough and meat	Quora, quoting Pizza Hut PDF
Domino's Supreme (Classic Crust, NZ)	190 kcal	Example of a potentially lighter version	fatsecret
Simple Simon's Supreme (Thick & Chewy Crust)	264 kcal	Varies by brand and specific recipe	Eat This Much
Generic Supreme (Average, US)	350–500+ kcal	Reflects a typical, loaded pizza	Curry Pizza House

How to Reduce Calories in Your Supreme Pizza

For those watching their calorie intake, there are several ways to enjoy the flavor of supreme pizza while minimizing the impact:

Choose Thin Crust: Opt for a thin crust over a deep-dish or stuffed crust to significantly lower the carbohydrate and fat base.
Focus on Veggies: Pile on low-calorie vegetables like mushrooms, onions, and peppers, and reduce the amount of high-fat meats.
Go Lighter on Cheese: Ask for less cheese or choose a lower-fat cheese option to cut down on saturated fat and calories.
Add Lean Protein: Use grilled chicken or lean ground turkey sausage instead of traditional pepperoni and high-fat sausage.
Pair with a Salad: Serve your pizza with a side salad to increase fiber and help you feel full faster, leading to a smaller portion size.

How Homemade Pizza Compares to Commercial Brands

Making pizza at home gives you complete control over the ingredients, allowing for precise calorie management. You can use whole wheat flour for the crust, pack on the vegetables, and use less oil and cheese than many commercial varieties. A homemade supreme pizza can be a much healthier and lower-calorie option compared to a heavily processed frozen or fast-food alternative.

Conclusion: The Final Slice on Supreme Pizza Calories

There is no one-size-fits-all answer to the question, "How many calories are in a single slice of supreme pizza?" The calorie count is a function of multiple variables, including crust type, portion size, and the generous combination of meaty and cheesy toppings. While a thin-crust slice could be under 300 calories, a large, thick-crust slice from a major chain could easily exceed 400 or even 500 calories. The best way to know for sure is to check the nutritional information provided by the specific restaurant or brand, or to build your own healthier version at home. Understanding these factors allows you to enjoy your pizza responsibly and make choices that align with your dietary goals. For more in-depth nutritional information on various foods, consult reliable sources like Healthline.

Frequently Asked Questions

The average can vary significantly, but a typical slice often falls between 350 and 500 calories, especially for large, regular-crust pizzas from chains.

Yes, a thin crust supreme pizza generally has fewer calories than a regular, hand-tossed, or deep-dish crust, as the base contributes less to the total caloric intake.

Processed meat toppings like pepperoni and sausage are high in fat and calories, significantly increasing the total calorie count of a supreme pizza compared to a purely vegetarian option.

While it can provide protein and other nutrients, a single slice of supreme pizza is often high in calories, sodium, and saturated fat. It should be enjoyed in moderation as part of a balanced diet rather than as a daily staple.

To estimate calories for a homemade supreme pizza, you need to calculate the calories for each ingredient separately, sum them, and then divide by the number of slices you cut.

Portion size is a huge factor. A slice from a large pizza cut into eight pieces will have more calories than a slice from the same pizza cut into 12 pieces.

One of the simplest ways to lower the calorie count is to request a thin crust and load up on extra vegetable toppings while reducing the amount of cheese and fatty meats.

No, frozen supreme pizzas can vary widely in calories, depending on the brand, crust type, and ingredients. Always check the nutrition facts on the packaging, as they can range from 300 to 450 calories or more per slice.