What Leading Health Organizations Say
Contrary to decades of misinformation, global health bodies and regulatory agencies have consistently affirmed the safety of monosodium glutamate (MSG) for the general population. Organizations like the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA) classify MSG as safe when used responsibly. Their conclusions are based on extensive scientific reviews that found no convincing evidence linking MSG to severe illness or negative health effects at typical dietary levels.
The Acceptable Daily Intake (ADI) Explained
The EFSA has set a group Acceptable Daily Intake (ADI) for glutamates, including MSG, at 30 mg per kg of body weight per day. This figure represents an amount that can be consumed daily over a lifetime without appreciable health risk. For an average 70kg adult, this translates to 2,100 mg per day, or 2.1 grams. This is a very generous amount, far exceeding typical daily intake from both added and naturally occurring sources.
Average vs. Excessive Intake
Average daily consumption of added MSG is estimated to be well below the established ADI. In the U.S. and U.K., for example, average intake is around 0.55 grams per day, while in Asian countries, it is slightly higher at 1.2–1.7 grams. This contrasts with the 3 grams or more required to potentially elicit mild, temporary symptoms in sensitive individuals, an amount rarely consumed in one sitting, especially without food. The key takeaway is that the amount consumed in a typical diet is not a concern for most people.
Natural vs. Added MSG: A Non-Issue
One common point of confusion is the difference between naturally occurring glutamate and added MSG. The human body metabolizes both in exactly the same way. Your body does not distinguish whether the glutamate comes from a shaker of MSG or is naturally present in foods like Parmesan cheese or tomatoes.
Foods Naturally High in Glutamate
- Cheeses: Especially aged cheeses like Parmesan.
- Tomatoes: Concentrated tomato products like paste have high levels.
- Mushrooms: Another source of naturally occurring glutamate.
- Soy Sauce: A fermentation-based sauce rich in glutamate.
- Seaweed: The original source from which MSG was isolated.
MSG Sensitivity and the “MSG Symptom Complex”
While MSG is safe for most, a very small subset of the population may experience mild, short-lived symptoms after consuming large, concentrated doses. This phenomenon, previously called “Chinese Restaurant Syndrome,” is now more accurately referred to as “MSG Symptom Complex”.
Potential Symptoms in Sensitive Individuals
Symptoms of MSG Symptom Complex can include headaches, flushing, sweating, nausea, and tingling or numbness. These symptoms are rare and typically only occur after consuming 3 grams or more of MSG on an empty stomach. The response is not an allergic reaction, and researchers have not consistently been able to reproduce these effects under controlled, double-blind study conditions.
MSG and Sodium Reduction
MSG contains significantly less sodium than table salt, about one-third the amount. This property has led to its use as a tool for sodium reduction in processed foods. By replacing a portion of table salt with MSG, manufacturers can maintain or even enhance the savory flavor profile of a product while decreasing its overall sodium content.
Sodium Content Comparison: Salt vs. MSG
| Flavor Enhancer | Sodium Content (per 100g) | Primary Use | Sodium Reduction Potential | Concerns |
|---|---|---|---|---|
| Table Salt | ~39.34g | Seasoning, preservative | No | High sodium intake linked to high blood pressure. |
| MSG | ~12.28g | Flavor enhancer | High (up to 37% or more) | Mild sensitivity in a very small subset of the population. |
Conclusion: The Final Word on MSG Safety
For the vast majority of people, MSG is a safe food additive that can be enjoyed without concern. Health authorities worldwide have deemed it generally safe, and the acceptable daily intake is far above what is typically consumed. The negative perception surrounding MSG is primarily based on outdated, poorly designed studies and anecdotal reports that have been debunked by modern research. Unless you are part of the very small group of individuals who experience mild, transient symptoms after consuming large amounts, there is no scientific reason to avoid MSG. In fact, it can be a useful tool for reducing overall sodium intake while preserving the savory flavors in your food. The key, as with all dietary components, is moderation within a balanced diet. If you believe you are sensitive, it is best to check food labels for 'monosodium glutamate' and other natural glutamate sources like yeast extract. For more detailed scientific findings, refer to the FDA's official Q&A on MSG.
A Final Perspective: The Source Matters
It's important to differentiate between added MSG and the highly processed, often high-sodium foods it is associated with, such as instant noodles, processed snacks, and fast food. The potential health risks of these foods often stem from their high fat, sugar, and sodium content, not the MSG itself. Therefore, focusing on a whole-food-based diet is a more effective approach to improving your overall health than simply avoiding MSG.
Disclaimer: This article is for informational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare professional regarding any dietary concerns or sensitivities.
How Much MSG Is Safe Per Day - Summary
- Officially Safe: Regulatory bodies like the FDA and EFSA classify MSG as 'generally recognized as safe' (GRAS) for the general population.
- Established ADI: The European Food Safety Authority (EFSA) sets an Acceptable Daily Intake (ADI) of 30 mg per kg of body weight per day.
- Typical Intake Is Low: Average consumption is significantly lower than the ADI, with most people consuming less than 1 gram of added MSG daily.
- Mild Sensitivity Is Rare: Only a small subset of the population (less than 1%) might experience mild, temporary symptoms after consuming large doses of MSG (over 3 grams) on an empty stomach.
- Added vs. Natural Is the Same: The body metabolizes naturally occurring glutamate (found in tomatoes, cheese) and added MSG identically.
- Sodium Reduction Aid: MSG can be used to reduce the sodium content of food while maintaining flavor, as it contains about one-third the amount of sodium as table salt.
- Controversy Based on Myths: The stigma against MSG stems from anecdotal reports and poorly conducted studies, not robust scientific evidence.