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How to dissolve oxalates in the body? Understanding prevention and treatment

4 min read

Calcium oxalate is the most common type of kidney stone, accounting for up to 80% of cases. While dissolving existing oxalate deposits in the body is not possible with simple remedies, effectively managing and preventing their formation is achievable through several proven strategies. This guide will explain how to manage oxalates in the body's digestive and urinary systems by preventing their crystallization and reducing your overall oxalate load.

Quick Summary

Effective management of oxalates involves key dietary adjustments, sufficient fluid intake, and sometimes, medical interventions. The goal is to bind oxalates in the gut and prevent crystal formation, not to dissolve pre-existing deposits.

Key Points

  • Dissolving vs. Preventing: Existing oxalate crystals and kidney stones cannot be dissolved by simple remedies; treatment focuses on preventing new crystals from forming.

  • Hydration is Paramount: Drinking plenty of water is the most effective way to flush the kidneys and dilute the urine, reducing the concentration of oxalates.

  • Pair Calcium and Oxalate: Consume dietary calcium, ideally with meals, to bind oxalates in the gut and prevent their absorption into the bloodstream.

  • Modify High-Oxalate Food Intake: While not always necessary, limiting intake of very high-oxalate foods like spinach, rhubarb, and nuts can help manage hyperoxaluria.

  • Use Proper Cooking Methods: Boiling and steaming can significantly reduce the soluble oxalate content of vegetables; remember to discard the cooking water.

  • Consider Supplements and Medications: Medical interventions like potassium citrate and probiotics may be recommended by a doctor for specific conditions.

  • Avoid High-Dose Vitamin C: Supplementing with high doses of vitamin C can increase oxalate production in the body and should be avoided by those at risk.

In This Article

Understanding Oxalates and Their Impact

Oxalate, or oxalic acid, is a naturally occurring compound found in many plants. When consumed, it binds with minerals, primarily calcium, in the digestive tract. These compounds typically leave the body through stool. However, when there's insufficient calcium to bind with the oxalate, the excess can be absorbed and excreted by the kidneys, where it can combine with calcium to form hard, crystalline deposits. These deposits are the basis for calcium oxalate kidney stones, and the condition of high urinary oxalate is known as hyperoxaluria.

Existing oxalate deposits, especially large kidney stones, cannot be simply "dissolved" with dietary changes or supplements alone. Medical procedures are required for removal. The focus of at-home strategies, therefore, is on preventing the formation of new crystals and limiting the growth of existing ones.

Primary Strategies for Managing Oxalate Buildup

Increase Fluid Intake to Flush the System

Drinking enough fluids is the single most effective action you can take to prevent oxalate crystal formation. High fluid intake increases urine volume, which dilutes the concentration of oxalate, calcium, and other minerals, making it much harder for crystals to form and aggregate.

Fluid intake recommendations:

  • Target Urine Output: Aim to produce at least 2.5 to 3 liters of urine per day, which for most people requires drinking around 10-12 glasses (approx. 100 ounces) of fluid daily.
  • Best Fluid Choices: Water is the best choice. Some citrus juices, particularly lemonade and orange juice, can also be beneficial as they contain citrate, which helps prevent calcium from binding with oxalate.
  • Monitor Your Intake: In hot weather or with strenuous exercise, your fluid needs will increase. Pay attention to urine color; a light yellow hue indicates proper hydration.

Pair Calcium with High-Oxalate Foods

This is a crucial and often misunderstood strategy. Instead of restricting calcium, it is vital to consume enough from dietary sources to bind oxalates in the intestines before they can be absorbed.

  • How it Works: When calcium and oxalate are eaten together, they bind in the digestive tract and are excreted in the stool, preventing high levels of oxalate from reaching the kidneys.
  • Best Sources: Focus on dietary calcium from foods like milk, yogurt, cheese, calcium-set tofu, and fortified plant-based milks.
  • Timing is Key: Eat calcium-rich foods alongside meals that contain higher amounts of oxalate. For example, add some cheese to a spinach-heavy salad.

Dietary Adjustments for Long-Term Control

Limit Very High-Oxalate Foods

While a low-oxalate diet is not necessary for everyone, restricting or moderating certain very-high-oxalate foods can be beneficial, especially for individuals with recurrent kidney stones.

High-oxalate foods to be mindful of:

  • Spinach, Swiss chard, and beet greens
  • Rhubarb and beets
  • Nuts, such as almonds and cashews, and nut butters
  • Chocolate and cocoa powder
  • Soy products, including tofu and soy milk
  • Wheat bran and wheat germ

Avoid High-Dose Vitamin C Supplements

High-dose vitamin C supplements (over 1,000 mg) can be converted to oxalate in the body, increasing the risk of stone formation. Getting vitamin C from dietary sources does not carry the same risk. Individuals prone to calcium oxalate stones should avoid large-dose supplements.

Reduce Sodium and Animal Protein

High sodium intake can increase calcium excretion in the urine, while excessive animal protein can raise uric acid levels, both of which increase the risk of stone formation.

  • Sodium: Aim for less than 2,300mg of sodium per day.
  • Protein: Moderate your intake of animal proteins like beef, pork, poultry, and fish.

The Role of Specific Cooking Techniques

Simple cooking methods can significantly reduce the oxalate content of some foods, particularly leafy greens.

  • Boiling: Boiling vegetables can remove a large percentage of soluble oxalates as they leach into the water. Always discard the cooking water afterwards.
  • Steaming: While less effective than boiling, steaming can also help reduce oxalate content.
  • Soaking and Fermenting: Soaking legumes overnight and fermenting vegetables like kimchi have also been shown to reduce oxalate levels.

The Potential of Supplements and Medical Treatments

For individuals with a history of recurrent stones or diagnosed hyperoxaluria, medical supervision is essential. Your doctor may recommend specific supplements or prescription medications.

  • Potassium Citrate: A potassium citrate supplement increases the body's citrate levels and raises urine pH, which helps to inhibit crystal growth and prevent stone formation.
  • Probiotics: Certain probiotics, particularly strains of Lactobacillus and Oxalobacter formigenes, have shown potential in degrading oxalate in the gut, reducing the amount absorbed by the body. A balanced gut microbiota is thought to be crucial for oxalate metabolism.
  • Pyridoxine (Vitamin B6): For those with certain types of primary hyperoxaluria, a prescription dose of vitamin B6 can help lower oxalate levels.

Comparison of Oxalate Management Strategies

Strategy Mechanism Best For Effectiveness Consideration
High Fluid Intake Dilutes urine, prevents crystal formation. Everyone, especially stone formers. High Needs consistent effort and monitoring.
Pairing Calcium Binds oxalate in the gut before absorption. Those managing dietary oxalate. High Need to get calcium from food

Frequently Asked Questions

No, lemon juice and apple cider vinegar do not dissolve existing oxalate deposits. The citrate in lemon juice can help prevent new crystals from forming by inhibiting calcium binding, but it will not break down existing stones.

For most people, a strict low-oxalate diet is not necessary and can lead to unnecessary dietary restrictions. The best approach is to manage intake by pairing high-oxalate foods with calcium-rich foods and staying hydrated.

The National Kidney Foundation recommends aiming for 1,000-1,200 mg of dietary calcium per day, obtained from food sources rather than supplements, to help bind oxalates in the gut.

Certain probiotic strains, particularly from the Lactobacillus family, have shown potential in animal and human studies to help degrade oxalates in the gut. However, more research is needed, and effectiveness can vary.

High-dose vitamin C supplements can increase urinary oxalate levels in some individuals, elevating the risk of forming calcium oxalate kidney stones. It is advisable to avoid excessive vitamin C supplementation, particularly if you are prone to stones.

No, other methods like steaming, soaking, and fermenting can also help reduce oxalate levels. Boiling is often the most effective method for leaching soluble oxalates into the water, which should then be discarded.

Medical treatments can include prescription medications like potassium citrate, pyridoxine (Vitamin B6) for specific types of hyperoxaluria, and in severe cases, more advanced therapies like RNAi drugs, dialysis, or transplants.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.