What is a PICC line?
A PICC line is a peripherally inserted central catheter. It's a long, thin tube made of flexible material that is inserted into a peripheral vein, typically in the arm. The catheter is threaded through the vein until its tip rests in a large central vein near the heart. This positioning is crucial because it allows highly concentrated substances, like total parenteral nutrition (TPN), to be diluted quickly by the high blood flow, preventing damage to smaller, more sensitive peripheral veins.
The use of PICC lines for parenteral nutrition
Parenteral nutrition (PN), including Total Parenteral Nutrition (TPN), is a liquid, nutrient-rich solution containing glucose, proteins, fats, vitamins, and minerals. It is administered to patients whose digestive system is not working correctly, for example, due to Crohn's disease, short bowel syndrome, severe vomiting, or post-surgical recovery. The PICC line offers a dependable, long-term vascular access solution for delivering this nutrition directly into the bloodstream. This eliminates the need for frequent and painful peripheral IV insertions, which are unsuitable for long-term use or for the high osmolarity of TPN.
Administration process for nutritional solutions
Administering nutrition through a PICC line requires a sterile and carefully monitored process. A bag of the nutritional solution is hung from an IV pole and connected to the external port of the PICC line. An infusion pump controls the rate at which the solution is delivered, often over a period of 10 to 12 hours, allowing patients to maintain their daily routine with minimal interruption. This nocturnal administration is a common practice, freeing up patients during the day. Healthcare providers ensure strict aseptic techniques are followed when accessing the line to minimize the risk of infection, a primary concern with any indwelling catheter.
Lists of common PICC line uses
- Total Parenteral Nutrition (TPN): Provides all the necessary nutrients when a patient cannot eat or absorb food through the gut.
- Long-Term Medications: Administers antibiotics or antifungal medications for weeks or months.
- Chemotherapy: Delivers chemotherapy drugs that would be too harsh for smaller peripheral veins.
- IV Fluids and Hydration: Provides fluids for patients unable to tolerate oral intake.
- Blood Transfusions: Used for administering blood products.
- Frequent Blood Draws: Reduces the need for repeated needle sticks for blood testing.
Care and maintenance
Proper care of a PICC line is critical to prevent complications such as infection, blood clots (thrombosis), or blockages. The dressing at the insertion site must be changed weekly, or sooner if it becomes wet or peels off, using sterile techniques. When not in use, the line must be flushed regularly, usually with saline, to prevent blockages. Patients or caregivers are taught how to perform these tasks, though district nurses can also assist with home care. Recognizing signs of complications, such as redness, swelling, fever, or pain, is vital for prompt medical intervention.
Comparison: PICC vs. Other Catheters for TPN
When considering central venous access for TPN, a healthcare team evaluates several factors, including the expected duration of treatment and the patient's condition. PICCs are often preferred for medium-term use (weeks to months), while other options might be better for shorter or longer periods.
| Feature | PICC Line | CVC (Central Venous Catheter) | Midline Catheter | 
|---|---|---|---|
| Insertion Site | Peripheral vein in the upper arm | Large central vein in the neck, chest, or groin | Peripheral vein in the arm, but ends before central veins | 
| Duration of Use | Medium-term (weeks to months) | Short-term or long-term, depending on type | Short-term (typically less than 4 weeks) | 
| TPN Suitability | Yes, excellent for TPN administration | Yes, also used for TPN, sometimes preferred for very long-term use | No, generally not suitable for TPN due to high osmolarity and risk of phlebitis | 
| Insertion Risk | Lower insertion risks (e.g., no pneumothorax) | Higher risk of insertion complications | Low insertion risk | 
| Home Use | Common for home care | Less common for home use compared to PICC | Sometimes used for shorter home IV therapy | 
Conclusion
In conclusion, a PICC line is an effective and common method for delivering parenteral nutrition, especially for patients who require medium-term intravenous feeding. By providing direct access to the central bloodstream, it ensures the safe administration of high-osmolarity nutritional solutions, bypassing a compromised gastrointestinal tract. While other central access options exist, the PICC line's balance of reliability, lower insertion risk, and suitability for home care makes it a valuable tool in modern medical care. For any patient receiving PN, a thorough understanding and adherence to the care protocol are essential for a successful outcome and to minimize complications. For more information on the standards of infusion therapy, refer to the Infusion Therapy Standards of Practice.
About the insertion procedure
The insertion of a PICC line is a routine medical procedure performed by a trained healthcare professional, often using ultrasound guidance to select the best vein. It typically takes less than an hour and involves a local anesthetic to numb the area, so it is generally not painful. The catheter is guided into the vein and its placement is confirmed with an x-ray or other imaging technology. After the procedure, the patient may feel some mild discomfort or soreness, but this subsides within a few days.
What is the total parenteral nutrition solution?
Total parenteral nutrition (TPN) is a complex and highly specialized solution. It is formulated by a pharmacist based on the patient’s individual nutritional needs, including their metabolic rate, weight, fluid balance, and blood test results. The solution contains a precise mixture of macronutrients (carbohydrates as glucose, proteins as amino acids, and lipids as fats) and micronutrients (vitamins, minerals, and electrolytes). This comprehensive formulation provides all the necessary components for the body to function, grow, and heal, effectively replacing oral intake. TPN differs from partial PN, which only supplements existing oral or enteral intake.
Potential risks and management
Like any medical device, PICC lines come with potential risks, though serious complications are relatively rare. The primary risks include infection, thrombosis (blood clots), and catheter malposition or damage. Strict adherence to aseptic technique during insertion and daily care is the most effective way to prevent infection. The risk of thrombosis is monitored through regular patient checks, and any symptoms of swelling or pain should be reported immediately. Healthcare professionals also check the external length of the catheter regularly to ensure it has not moved out of its correct position. Patient education and active participation in care are crucial for early detection and management of any potential problems.