Galactose, Lactose, and the Cheesemaking Process
To understand the galactose content in cheese, one must first grasp its relationship with lactose, the primary sugar in milk. Lactose is a disaccharide, meaning it is composed of two smaller sugar units: glucose and galactose.
When milk is made into cheese, a starter culture of lactic acid bacteria is introduced. These bacteria consume the lactose for energy, producing lactic acid. This fermentation process is what curds the milk and initiates the cheesemaking. The bacteria break down the lactose into its component parts, glucose and galactose. The extent to which these bacteria also consume the free galactose is the key factor determining the final galactose content of the cheese.
The Impact of Aging on Galactose Content
During the aging, or ripening, process, the bacteria continue to metabolize the remaining sugars. In mature and hard cheeses, this extended aging allows the lactic acid bacteria more time to consume almost all of the lactose and much of the free galactose. Research has consistently shown that many aged cheeses contain very low, or even negligible, levels of both lactose and galactose. Conversely, fresh cheeses that undergo minimal fermentation and aging, like ricotta or cottage cheese, retain much of their original lactose, and consequently, a higher concentration of galactose.
Why "Lactose-Free" Products Are Not Always Low-Galactose
A critical distinction exists between products labeled "lactose-free" and those that are naturally low in galactose. Lactose-free dairy products are created by adding the enzyme lactase to the milk, which breaks down the lactose into glucose and galactose before consumption. This process, while removing lactose, leaves behind significant amounts of free galactose. For individuals with classic galactosemia, a genetic disorder preventing the proper metabolism of galactose, these products are not safe and can be dangerously high in galactose.
The Role of Bacterial Strain in Fermentation
Not all lactic acid bacteria metabolize sugars the same way. Some strains are more efficient at breaking down galactose than others. For example, studies have shown that using specific galactose-fermenting strains can lead to lower residual galactose in cheese. Different starter cultures, aging temperatures, and even the milk's origin can influence the final sugar content of the cheese. This variability is why testing individual cheese batches is often recommended for those on strict low-galactose diets, such as individuals with galactosaemia.
List of Cheeses and Their Typical Galactose Levels
- Low Galactose Cheeses (Generally <25 mg/100g)
- Aged Cheddar (extra mature, vintage)
- Comté
- Emmental
- Gouda
- Gruyère
- Jarlsberg
- Parmigiano-Reggiano
- Pecorino Romano
 
- Higher Galactose Cheeses (Often significantly higher)
- Cottage Cheese
- Ricotta
- Fresh Mozzarella
- Soft Cheeses
- Processed Cheeses
 
Comparison Table: Galactose Content in Different Cheese Types
| Cheese Type | Aging Process | Fermentation | Typical Galactose Content (mg/100g) | Suitability for Galactosaemia | 
|---|---|---|---|---|
| Mature Cheddar | Long (9+ months) | Extensive | Very Low (<25 mg) | Generally Suitable | 
| Emmental/Swiss | Long | Extensive | Very Low (<25 mg) | Generally Suitable | 
| Fresh Mozzarella | Minimal | Minimal | High (>100 mg) | Not Suitable | 
| Cottage Cheese | Minimal | Minimal | High (>100 mg) | Not Suitable | 
| Processed Cheese | N/A | Variable | Very High (800+ mg) | Not Suitable | 
| Lactose-Free Cheese | Variable | Lactase-treated | High (>800 mg) | Not Suitable | 
A Note on Dietary Management and Galactosaemia
For individuals with galactosaemia, careful dietary management is essential. While many mature cheeses are considered safe due to their low residual galactose content, vigilance is still necessary. The exact galactose level can vary between brands and batches, so relying solely on the type of cheese can be risky. Some countries and organizations provide detailed lists of tested and approved cheeses that meet strict low-galactose standards. It is always recommended that individuals consult with a dietitian who can provide tailored nutritional advice based on specific needs and the availability of tested products.
The Functionality of Galactose in Cheese
Beyond dietary concerns, residual galactose has an interesting role in cheese development. For example, excess galactose can be a key factor contributing to the browning, or Maillard reaction, that occurs when certain types of cheese, such as mozzarella on pizza, are heated. This happens because the free galactose interacts with amino acids at high temperatures, creating the characteristic brown color. This is one reason why some cheesemakers employ specific bacterial strains that can metabolize the galactose to prevent discoloration and textural issues in their final product.
Conclusion
In short, while cheese does initially contain galactose as part of its lactose content, the level of galactose present in the final product is highly dependent on the cheesemaking process. Extensive fermentation and aging lead to significantly lower galactose content in hard, mature cheeses like Parmigiano-Reggiano and aged Cheddar, making them generally safe for those on a low-galactose diet. Conversely, fresh cheeses and 'lactose-free' products often contain surprisingly high levels of free galactose and should be avoided by individuals with galactosaemia. Understanding the science behind cheese production is vital for making informed dietary choices related to galactose intake. For more in-depth nutritional information and specific test results, resources like the National Institutes of Health (NIH) provide valuable scientific studies.