What is Severe Acute Malnutrition (SAM)?
Severe acute malnutrition (SAM) is a life-threatening condition resulting from recent and severe food restriction or illness. It is characterized by severe wasting, nutritional oedema, or both. The World Health Organization (WHO) and other international bodies define SAM using specific diagnostic criteria, primarily for children aged 6 to 59 months, though infants under six months are also highly vulnerable. A rapid decline in nutritional status can severely compromise the body's physiological functions and immune system, making a person highly susceptible to life-threatening infections. Early and effective management is crucial for survival and long-term health.
Diagnostic Criteria for SAM
According to WHO guidelines, SAM is diagnosed using a combination of anthropometric and clinical indicators. In children aged 6 to 59 months, the following are diagnostic features:
- Mid-Upper Arm Circumference (MUAC): A measurement less than 115 mm indicates SAM. MUAC is a highly effective and simple screening tool for identifying children at increased risk of mortality.
- Weight-for-Height Z-score (WHZ): A WHZ less than -3 standard deviations (SD) below the median of the WHO Child Growth Standards indicates severe wasting.
- Bilateral Pitting Oedema: The presence of bilateral pitting oedema (swelling, usually starting in the feet) is a clinical sign that automatically classifies a child as having SAM, irrespective of their WHZ or MUAC. This is a hallmark of the kwashiorkor form of malnutrition.
The Two Clinical Forms of SAM
Historically, SAM has been categorized into two main clinical presentations: marasmus and kwashiorkor. While modern treatment protocols often treat them similarly, understanding their distinctions is essential.
| Feature | Marasmus | Kwashiorkor | 
|---|---|---|
| Physical Appearance | Severely emaciated, skeletal appearance due to loss of muscle mass and fat. | Appears 'puffy' or swollen due to bilateral pitting oedema, especially in the hands, feet, and face. | 
| Underlying Deficiency | Deficiency of all macronutrients (carbohydrates, proteins, and fats), resulting from a lack of total calories. | Primarily a protein deficiency, though often seen in individuals with some carbohydrate intake. | 
| Weight | Very low weight for height (severe wasting). | Body weight can be deceptively high due to fluid retention, masking the underlying wasting. | 
| Other Signs | Apathy, poor growth, loss of subcutaneous fat. | Fatty liver, skin changes (pigmentation changes, ulceration), brittle hair, anaemia. | 
Causes and Risk Factors of SAM
The causes of SAM are complex and multifaceted, often involving a combination of immediate and underlying factors.
Immediate Causes
- Inadequate Dietary Intake: Insufficient energy, protein, and micronutrients are the direct nutritional causes. This can be due to food scarcity, poor-quality diet, or inappropriate feeding practices.
- Infections and Disease: Recurrent infections like diarrhoea, pneumonia, and measles are a major cause, as they increase nutrient requirements while decreasing appetite and absorption. HIV is also a contributing factor in many high-prevalence areas.
Underlying and Basic Causes
- Poverty and Food Insecurity: Limited financial resources lead to reduced access to nutritious food and healthcare services.
- Lack of Sanitation and Clean Water: Unhygienic conditions increase the risk of infectious diseases, trapping individuals in a vicious cycle of malnutrition and infection.
- Lack of Education: Low parental education is correlated with a higher risk of malnutrition in children.
- Family Size: Larger family sizes can strain household resources and contribute to food insecurity.
- Emergency Situations: Droughts, famine, conflicts, and natural disasters exacerbate food shortages and instability.
Treatment and Management of SAM
Modern management of SAM follows a phased, evidence-based approach, distinguishing between uncomplicated (outpatient) and complicated (inpatient) cases.
Inpatient Treatment for Complicated SAM
Children with medical complications or lack of appetite require hospitalization. The treatment process includes:
- Stabilization Phase (Days 1–7): Correcting life-threatening conditions like hypoglycaemia, hypothermia, and severe dehydration using specialized rehydration fluids like ReSoMal. This phase also involves treating infections with broad-spectrum antibiotics and correcting electrolyte imbalances. Feeding is initiated slowly with therapeutic milk (F-75).
- Transition Phase (Days 8-10): A short phase to transition the child to a higher-energy therapeutic food, often F-100 milk, while monitoring tolerance.
- Rehabilitation Phase (Weeks 2–6): Focuses on catch-up growth using high-energy ready-to-use therapeutic food (RUTF), like Plumpy'Nut. Iron supplementation is introduced at this stage.
Outpatient Treatment for Uncomplicated SAM
Children with a good appetite and no medical complications can be treated at home using RUTF, with regular check-ups. RUTF is a nutrient-dense, shelf-stable paste that is safe for consumption in non-refrigerated settings. The treatment course typically lasts 6 to 8 weeks until the child reaches sufficient weight gain and meets discharge criteria.
Prevention Strategies
Preventing SAM requires a multi-pronged approach addressing the underlying causes.
- Improved Infant and Young Child Feeding: Promoting exclusive breastfeeding for the first six months and appropriate complementary feeding practices is foundational.
- Better Access to Healthcare: Early detection and treatment of childhood illnesses can break the malnutrition-infection cycle.
- Enhanced Water, Sanitation, and Hygiene (WASH): Improving access to clean water and sanitation reduces the incidence of infections that contribute to malnutrition.
- Food Security and Livelihoods: Long-term strategies like supporting household food production and social protection programs are crucial for preventing malnutrition.
Conclusion
Understanding severe acute malnutrition is more than just memorizing flashcards on Quizlet; it requires appreciating the complex interplay of clinical signs, diagnostics, and humanitarian factors. Defined by severe wasting, oedema, or a very low MUAC, SAM is a medical emergency with high stakes. With proper diagnosis and treatment—whether inpatient for complicated cases or outpatient for uncomplicated ones using Ready-to-Use Therapeutic Foods—recovery is possible. Ultimately, addressing the root causes of poverty, food insecurity, and poor sanitation is key to preventing SAM and saving countless lives.
For further reading on SAM protocols and guidelines, consult the World Health Organization.