Understanding the Metabolic Changes When Fasting for 22 Hours
                                
                                
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                                    4 min read                                
                            
                                After approximately 18 to 24 hours of fasting, the body's primary energy source shifts significantly as its stored glycogen reserves become depleted. This metabolic change marks a deeper level of fasting than a standard overnight fast, triggering a cascade of physiological adaptations to sustain energy and promote cellular health.