How many calories in a 4x2 protein style? A complete nutritional breakdown
                                
                                
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                                    4 min read                                
                            
                                While In-N-Out does not officially list the '4x2' on its menu, a reliable estimate places its calorie count at approximately 670 calories when ordered protein style with the classic spread. This popular secret menu item substitutes the bun for lettuce, significantly altering its nutritional profile and macronutrient split compared to a standard burger.