How Does Nicotine Affect Enzymes?
                                
                                
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                                    4 min read                                
                            
                                According to a 2005 Scripps Research study, the liver enzyme CYP2A6 is responsible for metabolizing approximately 80% of nicotine, making it central to understanding tobacco addiction and dosage requirements. However, nicotine's effects extend beyond its own metabolism, with both direct and indirect influences on a wide array of enzymes throughout the body.