Tag: Aldob gene

Hereditary fructose intolerance (HFI) is a rare genetic disorder affecting approximately 1 in 20,000 individuals in many populations, caused by a deficiency of the enzyme required to metabolize fructose. This critical missing piece in the metabolic pathway is aldolase B, which prevents the proper breakdown of fructose from dietary sources and can lead to dangerous metabolic complications.

Hereditary Fructose Intolerance, a rare genetic disorder affecting an estimated 1 in 20,000 to 30,000 people globally, can be life-threatening if mismanaged. A specific enzyme deficiency causes fructose intolerance, leading to serious health complications if dietary fructose is not strictly avoided.