Tag: Aldolase b deficiency

Hereditary Fructose Intolerance (HFI) is a rare genetic disorder where the body cannot properly metabolize fructose due to a deficiency of the enzyme aldolase B. This leads to a build-up of toxic fructose-1-phosphate, causing severe metabolic disturbances, liver damage, and kidney issues.

Affecting an estimated 1 in 20,000 to 30,000 individuals, hereditary fructose intolerance (HFI) is a rare genetic disorder that can become life threatening if left untreated following the ingestion of fructose. This dangerous condition is caused by a metabolic defect that triggers a cascade of toxic effects on the body's vital organs.