What is the cofactor for ALT?
                                
                                
                                •
                                
                                
                        
                                    
                                    4 min read                                
                            
                                An estimated 10% of people in the United States have abnormally high alanine aminotransferase (ALT) levels, and the enzyme's activity is critically dependent on a specific molecule for proper function. The cofactor for ALT is pyridoxal phosphate, the biologically active form of vitamin B6, which is crucial for the enzyme's role in amino acid metabolism.