Does annatto extract have side effects? A comprehensive guide
                                
                                
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                                    4 min read                                
                            
                                While generally considered safe for most people in food amounts, some studies indicate that annatto extract can cause allergic reactions in sensitive individuals, with one 1978 study showing 26% of urticaria patients reacting to it. It is important to understand the potential side effects associated with this common natural food coloring.