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Tag: Antifolate drugs

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What Inhibits Folate Synthesis? Understanding Antifolate Mechanisms

4 min read
Unlike humans, who must obtain folate from their diet, many microorganisms, such as bacteria and protozoa, must synthesize it internally, making their folate pathway a prime target for antimicrobial agents. This article explores what inhibits folate synthesis in various organisms and the mechanisms behind these crucial medical interventions.