Tag: Antioxidant side effects

While often touted for its antioxidant properties, studies suggest that some individuals taking oral glutathione supplements, including a 1000 mg dosage, may experience gastrointestinal issues such as bloating and cramping. Understanding these potential reactions is crucial before starting any new supplement regimen.

A 2023 study published in the journal *Antioxidants* highlighted that excessive antioxidant intake can, paradoxically, be harmful and ineffective, with higher doses sometimes leading to adverse effects. So, what happens if I eat too much antioxidants, and is it a case of too much of a good thing?

According to a 2024 study in *Frontiers in Nutrition*, higher dietary antioxidant intake is often associated with a lower risk of constipation, particularly in men. Despite this, a common concern among supplement users is whether antioxidants can cause constipation, a side effect reported with certain vitamins and minerals, especially in high doses. This article investigates the surprising exceptions and contributing factors behind this digestive issue.

In a 2012 meta-analysis involving over 230,000 participants, researchers found that high-dose supplementation with beta-carotene, vitamin A, and vitamin E was associated with an increased risk of mortality. This evidence highlights that while dietary antioxidants are beneficial, excess intake, especially from supplements, can lead to side effects.

While vitamin E is a vital antioxidant, research indicates that excessive intake from supplements can increase the risk of serious side effects like bleeding and hemorrhagic stroke. This raises the critical question: can you get too much of vitamin E?

While antioxidants are beneficial for neutralizing harmful free radicals, overwhelming evidence suggests that high-dose, super antioxidant supplements can have adverse effects and may even increase mortality in some populations. Understanding the potential side effects is crucial for anyone considering adding these supplements to their diet.