Tag: B12 deficiency mask

A 2008 study found that the synthetic form, folic acid, has a tolerable upper intake limit of 1,000 mcg per day due to potential risks. This raises a critical question: can you take too much active folate, also known as L-methylfolate?

According to the NIH Office of Dietary Supplements, the Tolerable Upper Intake Level (UL) for synthetic folic acid in adults is 1,000 micrograms (mcg) per day. This guideline helps to answer the crucial question of just how high is too high for folic acid, which, when taken in excess through supplements and fortified foods, can pose certain health risks.

According to the NIH, approximately 5% of adults aged 51–70 who use dietary supplements consume over 1,000 mcg of folic acid daily. While beneficial in recommended doses, consuming too much folate in your system, especially from synthetic folic acid, can pose significant health risks that many people are unaware of.

According to the Office on Women's Health, taking more than 1,000 micrograms of folic acid daily can have negative health consequences, including masking a vitamin B12 deficiency. This is one of the most significant concerns regarding the overconsumption of vitamin B9, but other short-term side effects and long-term risks exist.