What is the vitamin B6 paradox? Understanding High-Dose Supplementation
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4 min read
According to a 2017 study, supplementing with high concentrations of the inactive form of vitamin B6, pyridoxine, can paradoxically lead to decreased vitamin B6 function, which defines the vitamin B6 paradox. This occurs because excess pyridoxine can actually block the active form of the vitamin, leading to symptoms associated with deficiency, even at high intake levels.
