Tag: Bergamottin

First isolated from bergamot oil in 1937, bergamottin is a natural compound found predominantly in certain citrus fruits. This furanocoumarin is well-known for its potential to inhibit the cytochrome P450 enzyme CYP3A, which can significantly affect the metabolism of a variety of prescription drugs. Knowing what fruits have bergamottin is crucial for anyone taking medications that carry a 'grapefruit warning'.

Over 90% of the world's bergamot is produced exclusively in the Calabria region of Southern Italy due to its unique microclimate. The therapeutic properties of this citrus fruit are attributed to a diverse profile of active ingredients, which differ depending on whether the extract is taken from the juice or the peel's essential oil.