What happens to your body after eating a big meal?
                                
                                
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                                    4 min read                                
                            
                                It takes approximately 20 minutes for your stomach to signal your brain that you are full, meaning many people have overeaten before the feeling of fullness even sets in. Once a large meal is consumed, your body initiates a complex physiological response to process the excess food and calories. Understanding this process can help explain the feelings of discomfort, fatigue, and satisfaction that follow a hearty feast.