Tag: Biotin clearance

For patients on high-dose biotin supplements, laboratories often recommend abstaining for at least 72 hours before a blood draw to prevent inaccurate test results. As a water-soluble vitamin, biotin is rapidly processed by the body, but several factors influence the time it takes to get biotin out of your system completely.

The human body naturally produces biotin, a water-soluble B vitamin, and a healthy gut microbiome can often supply more than the body's needs. However, supplemental doses, especially high ones, can interfere with common laboratory tests, making it essential to understand **how long does it take to stop taking biotin** before undergoing medical evaluations.

As a water-soluble vitamin, excess biotin is not stored in the body and is instead excreted primarily through the kidneys. In healthy adults taking standard doses, biotin has a circulating half-life of approximately two hours, but the answer to the question, "How fast does biotin leave the body?", is more complex for those taking high-dose supplements.