Tag: Buccal mucosa

While digestion begins the moment food enters your mouth with the mechanical action of chewing and the release of enzymes, the question of whether you absorb sugar in the mouth is a common point of confusion. Although some minimal absorption can occur, the mouth is not a primary organ for this process.

According to scientific studies, caffeinated chewing gum can lead to a peak plasma concentration of caffeine in as little as 44–80 minutes, significantly faster than traditional capsules. This rapid onset is because yes, caffeine is absorbed through the gums and other oral tissues, a process known as buccal absorption.

According to pharmacokinetic studies, the absorption of caffeine from chews can begin in as little as 3 to 5 minutes, offering a significantly faster onset than traditional beverages. The question, "**How long do caffeine chews take to kick in?**" is best answered by understanding the unique absorption pathway that makes them so effective.