Is the Buckeye Plant Edible for Humans? Understanding the Dangers
                                
                                
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                                    4 min read                                
                            
                                According to the USDA Plants Database, all parts of the Ohio buckeye tree are highly toxic if ingested due to the presence of glycoside aesculin and saponin aescin. This means that the answer to 'Is the buckeye plant edible for humans?' is a definitive and absolute no.