Tag: Caffeine genetics

According to scientific estimates, the heritability of caffeine-related traits ranges between 35% and 77%. This significant genetic component explains why some individuals can drink an espresso before bed without issue, while others get jitters from a small cup of tea, and whether caffeine tolerance can be genetic.

According to a study published in the journal *Psychopharmacology*, approximately 10–20% of the population experiences heightened sensitivity to caffeine. This heightened reaction, leading to jitters and anxiety, can be caused by genetic variations and differences in how the body processes the stimulant.

The average half-life of caffeine in a healthy adult is approximately 5 to 6 hours, meaning it takes that long for half of the initial dose to be eliminated. Understanding exactly how long does caffeine live in your body is crucial for managing its stimulant effects and avoiding disruptions to your sleep and health.

Did you know that about 50% of the population are 'fast' caffeine metabolizers due to their genetics? This is a primary reason for those who ask, 'why doesn't caffeine affect me?' even after drinking several cups. The answer lies in a complex interplay of inherited traits and lifestyle habits.

According to research, around 10% of people carry a gene that makes them hyposensitive to caffeine. For many, the expectation of a quick energy boost from a cup of coffee falls flat, leading to questions about whether it's normal to not feel the effects of caffeine.