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Tag: Calcidiol half life

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How long does 5000 IU of vitamin D stay in your system?

4 min read
The primary circulating form of vitamin D, 25-hydroxyvitamin D (calcidiol), has a half-life in the bloodstream of approximately 15 days. For a 5000 IU dose, the vitamin D itself is rapidly cleared from the blood within days, but the body stores a significant portion in fat cells, releasing it slowly over weeks or even months. This means a single high dose can have a prolonged effect on your vitamin D levels, a feature that depends heavily on individual factors.