Understanding Why and How: Can TPN Go Through a Cannula?
                                
                                
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                                    3 min read                                
                            
                                According to the American Society for Parenteral and Enteral Nutrition (ASPEN), the osmolarity of solutions infused peripherally should be limited to 900-1000 mOsm/L to prevent vein irritation. This critical limitation is the core reason the direct answer to 'Can TPN go through a cannula?' is no, because Total Parenteral Nutrition (TPN) solutions are highly concentrated and far exceed this threshold.