Tag: Catheter related bloodstream infection

According to the Centers for Disease Control and Prevention (CDC), meticulous infection control is essential for patients receiving Total Parenteral Nutrition (TPN) to minimize the risk of catheter-related bloodstream infections. This is precisely why TPN tubing is changed every 24 hours, a crucial measure to counteract the heightened risk of microbial growth within the nutrient-rich solution.

According to a study of hospitalized patients, over a third developed a bloodstream infection (BSI) while receiving parenteral nutrition (PN). The most common complication of parenteral nutrition use is infection, specifically catheter-related bloodstream infections (CRBSIs), due to the indwelling central venous catheter required for this therapy. These infections are serious and can significantly increase morbidity and mortality risks.

According to a 2019 study, Total Parenteral Nutrition (TPN) remains an independent risk factor for central line-associated bloodstream infections (CLABSIs), which can lead to sepsis. Understanding why TPN causes sepsis is crucial for both healthcare providers and patients receiving this life-sustaining treatment. The risk is primarily linked to the central venous catheter used for administration and the physiological changes bypassing the gut.