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Tag: Cellular mechanisms

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The Theory Behind Calorie Restriction and Longevity

3 min read
Over eight decades of research, starting with animal studies in the 1930s, have revealed that calorie restriction (CR) can extend lifespan and healthspan in many species. What is the theory behind calorie restriction that explains this profound effect? The primary theory suggests that reducing energy intake without causing malnutrition activates key cellular pathways and metabolic shifts that enhance the body's resilience and delay the aging process.