Tag: Citrin deficiency

The term “citrin” refers to different substances depending on the context, with a key example being a crucial protein in human metabolism and a distinct commercial weight-loss supplement. It is essential to distinguish between these disparate entities to avoid dangerous health misconceptions and understand what an ingredient citrin is.

Many people search for what foods contain citrin, but the truth is that citrin is a protein in your body, not a compound found in food. It's a key transporter in the liver's mitochondrial membrane, and issues with this protein lead to the rare genetic condition known as citrin deficiency.

L-citrulline deficiency typically signals an underlying genetic metabolic disorder, such as citrullinemia, impacting roughly 1 in 57,000 individuals globally. This condition disrupts detoxification, leading to ammonia buildup and a range of symptoms depending on the age of onset.