Tag: Citrulline benefits

Initially found in watermelon, L-citrulline is a non-essential amino acid that plays a key role in boosting nitric oxide levels. This makes the L-citrulline supplement particularly good for those looking to enhance blood flow for exercise and cardiovascular health.

Research indicates that L-citrulline supplementation can lead to peak plasma arginine levels within 1-2 hours, suggesting a relatively rapid onset of effects [1]. Understanding the longevity of this supplement requires looking beyond initial absorption. So, how many hours does L-citrulline last, and what influences its staying power within the body? This comprehensive guide explains everything you need to know.

While often discussed alongside one another, a 2025 study highlighted that creatine and citrulline have fundamentally distinct mechanisms for enhancing athletic performance. Many fitness enthusiasts confuse the roles of these supplements, though they operate in complementary ways to improve different aspects of a workout.

According to scientific studies, L-citrulline has shown gastroprotective effects and can help improve the gut barrier, suggesting potential benefits for a healthy stomach. However, some individuals may experience gastrointestinal upset from supplements, particularly at high doses.