Is Citrulline Like Creatine? Understanding the Key Differences
                                
                                
                                •
                                
                                
                        
                                    
                                    3 min read                                
                            
                                While often discussed alongside one another, a 2025 study highlighted that creatine and citrulline have fundamentally distinct mechanisms for enhancing athletic performance. Many fitness enthusiasts confuse the roles of these supplements, though they operate in complementary ways to improve different aspects of a workout.