Is Grapefruit a CYP450 Inhibitor or Inducer? Explaining the Drug Interaction
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4 min read
According to the FDA, grapefruit juice and some common drugs don't mix, with over 85 medications identified as having potential interactions. The answer to whether grapefruit is a CYP450 inhibitor or inducer is clear: it acts as a potent inhibitor, primarily targeting the CYP3A4 enzyme in the gut. This interference can lead to an unexpected and potentially dangerous increase in drug concentration in the bloodstream.
