How many calories are in a slice of Devil's food cake?
                                
                                
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                                    3 min read                                
                            
                                A slice of store-bought Devil's food cake with frosting can have approximately 280 calories, though this can vary significantly based on ingredients and serving size. The exact calorie count for a slice of Devil's food cake depends on several factors, including the recipe used, whether it's homemade or from a mix, and the amount and type of frosting.