Why is Cyanosis Absent in Severe Anemia? A Medical Paradox Explained
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3 min read
While it may seem counterintuitive, severely anemic patients, who have very low oxygen-carrying capacity, do not exhibit the bluish skin discoloration known as cyanosis. This clinical paradox occurs because the visible sign of cyanosis depends on the absolute concentration of deoxygenated hemoglobin, not the percentage of oxygen saturation.