Is there a disease that makes it hard to gain weight?
                                
                                
                                •
                                
                                
                        
                                    
                                    4 min read                                
                            
                                Many people struggle to gain weight despite their best efforts, but for some, the cause is an underlying health issue. Unexplained weight loss is often a red flag, and yes, there are diseases that can make it hard to gain weight, impacting metabolism, nutrient absorption, and appetite.