Tag: Drug efficacy

According to the National Institutes of Health, only the unbound or "free" fraction of a drug is pharmacologically active and can exert a therapeutic effect. This is precisely why protein-bound drug breakdown, or more accurately, dissociation, is a cornerstone of effective drug therapy and patient safety.

According to research, increasing dietary fiber offers significant health benefits, but it is crucial to understand potential interactions with other substances. Therefore, it is important to know what you shouldn't take fiber with to prevent potential health issues or reduced medication efficacy.

Bioavailability, the rate and extent to which an active substance enters systemic circulation, can vary dramatically, with intravenous drugs achieving 100% bioavailability while oral counterparts can be significantly lower. This fact underscores the importance of strategies to increase bioavailability for both pharmaceuticals and nutritional supplements, ensuring maximum effectiveness once inside the body.