Tag: Endoplasmic reticulum stress

For decades, dietary guidelines have advised limiting saturated fat intake, and a 2019 UK Scientific Advisory Committee on Nutrition report linked higher consumption to raised blood cholesterol and cardiovascular disease risk. This article delves into the core biochemistry explaining why these fats negatively affect our cellular and metabolic functions.

Tauroursodeoxycholic acid (TUDCA) is a hydrophilic bile acid that has been used in traditional Chinese medicine for over 3,000 years, originally sourced from bear bile. Today, it is primarily produced synthetically and is known for its potent cytoprotective, or cell-protecting, properties across a wide range of organs and systems. It is the taurine-conjugated form of ursodeoxycholic acid (UDCA), a compound with established therapeutic uses for certain liver diseases.