Tag: Enos

The gas nitric oxide (NO) is a crucial signaling molecule involved in dilating blood vessels and regulating blood pressure. This has led to the important question: does resveratrol increase nitric oxide and how does it achieve this effect at a molecular level?.

Research published in the journal *Biomedicine & Pharmacotherapy* has shown that the flavonoid rutin can restore nitric oxide (NO) production in endothelial cells under high glucose stress. This finding, however, only tells one part of a complex story about whether rutin increase nitric oxide. The effect of this plant compound is highly dependent on the cellular environment and the specific type of nitric oxide synthase involved.