Does Synephrine Actually Work for Weight Loss?
                                
                                
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                                    3 min read                                
                            
                                Following the 2004 FDA ban on ephedrine-containing dietary supplements, synephrine, an alkaloid from bitter orange, became a popular weight-loss alternative. Despite its prevalence in thermogenic and performance products, the question remains: does synephrine actually work, and is it safe for long-term use?