What would happen if you ate 100,000 calories at once? The Medical Reality
                                
                                
                                •
                                
                                
                        
                                    
                                    4 min read                                
                            
                                According to medical experts, the human stomach can typically hold only about 1 to 1.5 liters of food, making the consumption of 100,000 calories in a single sitting a physical impossibility. So, what would happen if you ate 100,000 calories at once in a hypothetical scenario? The outcome would be nothing short of catastrophic.