Tag: Factor ii

Approximately 17 human proteins, including several key components of the coagulation cascade, depend on vitamin K for proper activation. This fat-soluble vitamin acts as an essential cofactor for the enzyme gamma-glutamyl carboxylase, which enables critical blood proteins to bind calcium and function correctly. When considering which clotting factors are affected by vitamin K, it is important to understand that its influence extends to both procoagulant and anticoagulant proteins.

Affecting approximately one in every two million people, factor 2 deficiency is a rare bleeding disorder that hinders the body's ability to clot blood effectively. This condition, also known as prothrombin deficiency, occurs when the body produces insufficient or dysfunctional prothrombin, a critical protein for forming a stable blood clot.