Does Caffeine Lose Potency Overnight? The Chemical Truth
                                
                                
                                •
                                
                                
                        
                                    
                                    4 min read                                
                            
                                As one of the world's most widely consumed psychoactive substances, caffeine is a daily ritual for countless people. This reliance often leads to questions about its stability, especially concerning leftover coffee. The good news is that for anyone asking, "Does caffeine lose potency overnight?", the straightforward chemical answer is no. The perceived change in strength is a matter of taste, not chemistry.