Can Some People Not Handle Creatine? A Look at Non-Responders and Intolerance
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5 min read
While creatine is widely considered a safe and effective supplement, some estimates suggest that as many as 20-30% of individuals may be creatine non-responders, experiencing minimal to no benefits from supplementation. The question of whether some people simply cannot handle creatine delves into genetic predispositions, individual physiology, and initial muscle creatine levels.
